Recombinant Human SVIP, His-tagged
Cat.No. : | SVIP-140H |
Product Overview : | SVIP, 1-77aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | Small VCP/p97-interacting protein, also known as SVIP, is involved in a variety of cellular processes, including membrane fusion and ubiquitin-dependent protein degradation. SVIP functions as an inhibitor of the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Overexpression of SVIP, on the other hand, increased the levels of p62 protein and enhanced starvation-activated autophagy as well as promoted sequestration of polyubiquitinated proteins and p62 in autophagosomes. Recombinant human SVIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 2mM DTT |
Molecular Mass : | 10.8kDa (100aa) confirmed by MALDI-TOF |
Protein length : | 1-77aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMGLCFPC PGESAPPTPD LEEKRAKLAE AAERRQKEAA SRGILDVQSV QEKRKKKEKI EKQIATSGPP PEGGLRWTVS |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Gene Name : | SVIP small VCP/p97-interacting protein [ Homo sapiens ] |
Official Symbol : | SVIP |
Gene ID : | 258010 |
mRNA Refseq : | NM_148893.1 |
Protein Refseq : | NP_683691.1 |
UniProt ID : | Q8NHG7 |
Chromosome Location : | 11p14.2 |
Pathway : | Protein processing in endoplasmic reticulum, organism-specific biosystem;Protein processing in endoplasmic reticulum, conserved biosystem; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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