"GDI1" Related Products

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Recombinant Human GDI1, His-tagged

Cat.No.: GDI1-196H
Product Overview: GDI1, 1-447aa, Human, His tag, E.coli
Description: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. Recombinant human GDI1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Molecular Mass: 53.0kDa (470aa)
Protein length: 1-447aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDEEYDV IVLGTGLTEC ILSGIMSVNG KKVLHMDRNP YYGGESSSIT PLEELYKRFQ LLEGPPESMG RGRDWNVDLI PKFLMANGQL VKMLLYTEVT RYLDFKVVEG SFVYKGGKIY KVPSTETEAL ASNLMGMFEK RRFRKFLVFV ANFDENDPKT FEGVDPQTTS MRDVYRKFDL GQDVIDFTGH ALALYRTDDY LDQPCLETVN RIKLYSESLA RYGKSPYLYP LYGLGELPQG FARLSAIYGG TYMLNKPVDD IIMENGKVVG VKSEGEVARC KQLICDPSYI PDRVRKAGQV IRIICILSHP IKNTNDANSC QIIIPQNQVN RKSDIYVCMI SYAHNVAAQG KYIAIASTTV ETTDPEKEVE PALELLEPID QKFVAISDLY EPIDDGCESQ VFCSCSYDAT THFETTCNDI KDIYKRMAGT AFDFENMKRK QNDVFGEAEQ
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml (determined by Bradford assay)
Gene Name: GDI1 GDP dissociation inhibitor 1 [ Homo sapiens ]
Official Symbol: GDI1
Synonyms: GDI1; GDP dissociation inhibitor 1; GDIL, MRX41, MRX48; rab GDP dissociation inhibitor alpha; FLJ41411; mental retardation; X linked 41; X linked 48; OPHN2; rab GDP dissociation inhibitor; alpha; RABGDIA; XAP 4; GDI-1; protein XAP-4; rab GDI alpha; oligophrenin-2; mental retardation, X-linked 48; rab GDP-dissociation inhibitor, alpha; guanosine diphosphate dissociation inhibitor 1; 1A; GDIL; MRX41; MRX48; XAP-4; RABGD1A;
Gene ID: 2664
mRNA Refseq: NM_001493
Protein Refseq: NP_001484
MIM: 300104
UniProt ID: P31150
Chromosome Location: Xq28
Pathway: Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem; Signaling mediated by p38-alpha and p38-beta, organism-specific biosystem;
Function: GDP-dissociation inhibitor activity; GTPase activator activity; Rab GDP-dissociation inhibitor activity; protein binding;

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