Active Recombinant Human CD70, His-tagged
Cat.No. : | CD70-116H |
Product Overview : | Recombinant Human CD70, contains the extracellular domain plus an N-terminal His-Tag, was expressed in CHO cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. |
Source : | CHO cells |
Species : | Human |
Tag : | His |
Bio-activity : | Determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/ml. Note: Results may vary with PBMC donors. |
AA Sequence : | HHHHHHHHPS PGGSGGQRFA QAQQQLPLES LGWDVAELQL NHTGPQQDPR LYWQGGPALG RSFLHGPELD KGQLRIHRDG IYMVHIQVTL AICSSTTASR HHPTTLAVGI CSPASRSISL LRLSFHQGCT IASQRLTPLA RGDTLCTNLT GTLLPSRNTD ETFFGVQWVR P |
Purity : | Greater than 95% by SDS-PAGE gel and HPLC analyses. |
Gene Name : | CD70 CD70 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD70 |
Synonyms : | CD70; CD27L; CD27LG; TNFSF7; CD70 molecule; CD70 antigen; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7 |
Gene ID : | 970 |
mRNA Refseq : | NM_001252 |
Protein Refseq : | NP_001243 |
MIM : | 602840 |
UniProt ID : | P32970 |
Chromosome Location : | 19p13 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | cytokine activity; protease binding; protein binding |
Products Types
◆ Recombinant Protein | ||
CD70-0851H | Recombinant Human CD70 Protein, GST-Tagged | +Inquiry |
CD70-324H | Active Recombinant Human CD70 Protein (Gln39-Pro193), N-His tagged, Animal-free, Carrier-free | +Inquiry |
CD70-545H | Recombinant Human CD70 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cd70-2065M | Recombinant Mouse Cd70 Protein, Myc/DDK-tagged | +Inquiry |
CD70-623H | Recombinant Human CD70 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CD70-2710HCL | Recombinant Human CD70 cell lysate | +Inquiry |
CD70-1303RCL | Recombinant Rat CD70 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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