Recombinant Human SIRT7, Flag-tagged
Cat.No. : | SIRT7-12H |
Product Overview : | Recombinant Human SIRT7, fused with C-terminal Flag tag, was expressed in an E. coli cell expression system. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. |
Source : | E. coli |
Species : | Human |
Tag : | Flag |
Form : | 45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl and 10% glycerol. |
Molecular Mass : | 46 kDa |
Purity : | ≥60% |
Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Stability : | >6 months at –80°C |
Gene Name : | SIRT7 sirtuin 7 [ Homo sapiens (human) ] |
Official Symbol : | SIRT7 |
Synonyms : | SIRT7; SIR2L7; sirtuin 7; NAD-dependent protein deacetylase sirtuin-7; sirtuin type 7; SIR2-like protein 7; sir2-related protein type 7; regulatory protein SIR2 homolog 7; NAD-dependent deacetylase sirtuin-7; silent mating type information regulation 2, S.cerevisiae, homolog 7; NP_057622.1; EC 3.5.1.- |
Gene ID : | 51547 |
mRNA Refseq : | NM_016538 |
Protein Refseq : | NP_057622 |
MIM : | 606212 |
UniProt ID : | Q9NRC8 |
Chromosome Location : | 17q25 |
Pathway : | Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Class III |
Function : | NAD+ binding; NAD-dependent histone deacetylase activity (H3-K18 specific); chromatin binding |
Products Types
◆ Recombinant Protein | ||
SIRT7-2016H | Recombinant Human SIRT7 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIRT7-5069R | Recombinant Rat SIRT7 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIRT7-21H | Recombinant Human SIRT7 Protein, His-tagged | +Inquiry |
SIRT7-120H | Recombinant Human SIRT7 Protein, His-tagged | +Inquiry |
SIRT7-8184M | Recombinant Mouse SIRT7 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SIRT7-1828HCL | Recombinant Human SIRT7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket