Recombinant Human PARP12, His-GST tagged

• Cat.No.: PARP12-433H
• Product Overview: Recombinant Human PARP12 (a.a. 500-701), fused with N-terminal His-GST tag, was expressed in a Baculovirus infected Sf9 cell expression system.

Specification

• Description: Poly (ADP-ribose) polymerase (PARP) is a protein involved in a number of cellular processes involving mainly DNA repair and programmed cell death.
• Source: Sf9 cell
• Species: Human
• Tag: His&GST
• Form: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 8mM Glutathione, 0.04% Tween20, and 20% glycerol.
• Molecular Mass: 51 kDa
• AA Sequence: MHHHHHHGGGSPILGYWKIKGLVQP TRLLLEYLEEKYEEHLYERDEGDKW RNKKFELGLEFPNLPYYIDGDVKLT QSMAIIRYIADKHNMLGGCPKERAE ISMLEGAVLDIRYGVSRIAYSKDFE TLKVDFLSKLPEMLKMFKDRLCHKT YLNGDHVTHPDFMLYDALDVVLYMD PMCLDAFPKLVCFKKRIEAIPQIDK YLKSSKYIAWPLQGWQATFGGGDHP PKSDPENLYFQGGGEFKITLSSSSE EYQKVWNLFNRTLPFYFVQKIERVQ NLALWEVYQWQKGQMQKQNGGKAVD ERQLFHGTSAIFVDAICQQNFDWRV CGVHGTSYGKGSYFARDAAYSHHYS KSDTQTHTMFLARVLVGEFVRGNAS FVRPPAKEGWSNAFYDSCVNSVSDP SIFVIFEKHQVYPEYVIQYTTSSKP SVTPSILLALGSLFSSRQ
• Purity: ≥90%
• Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Stability: >6 months at –80°C

Gene Information

• Gene Name: PARP12 poly (ADP-ribose) polymerase family, member 12 [ Homo sapiens (human) ]
• Official Symbol: PARP12
• Synonyms: PARP12; ZC3H1; ARTD12; MST109; MSTP109; ZC3HDC1; poly [ADP-ribose] polymerase 12; zinc finger CCCH type domain containing 1; zinc finger CCCH domain-containing protein 1; ADP-ribosyltransferase diphtheria toxin-like 12; NP_073587.1; EC 2.4.2.30
• Gene ID: 64761
• mRNA Refseq: NM_022750
• Protein Refseq: NP_073587
• MIM: 612481
• UniProt ID: Q9H0J9
• Chromosome Location: 7q34
• Function: NAD+ ADP-ribosyltransferase activity; metal ion binding