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Recombinant Human JUN, His-tagged

Cat.No.: JUN-8483H
Product Overview: Recombinant Human JUN was expressed as 6*his-tagged fusion protein by E.Coli and puri?ed by Ni-sepharose.
Description: This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Source: E.coli
Species: Human
Tag: His
Protein length: True
AA Sequence: 1-331aa
Storage: The protein is stored in PBS bu?er at -20 oC. Repeated freeze-thaw cycles should be avoided.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: JUN jun proto-oncogene [ Homo sapiens (human) ]
Official Symbol: JUN
Synonyms: JUN; AP1; AP-1; c-Jun; jun proto-oncogene; transcription factor AP-1; p39; jun oncogene; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog
Gene ID: 3725
mRNA Refseq: NM_002228
Protein Refseq: NP_002219
MIM: 165160
UniProt ID: P05412
Chromosome Location: 1p32-p31
Pathway: AGE/RAGE pathway; Activated TLR4 signalling; B Cell Receptor Signaling Pathway
Function: DNA binding; HMG box domain binding; RNA polymerase II activating transcription factor binding

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