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Recombinant Human phospholipid scramblase 1, His-tagged

Cat.No.: PLSCR1-354H
Product Overview: PLSCR1, 1-288aa, Human, His tag, E.coli
Description: Phospholipid scramblase 1, also known as PLSCR1, may play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. This protein may contribute to cytokine-regulated cell proliferation and differentiation. Recombinant human PLSCR1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT
Molecular Mass: 33.8 kDa (308aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MDKQNSQMNA SHPETNLPVG YPPQYPPTAF QGPPGYSGYP GPQVSYPPPP AGHSGPGPAG FPVPNQPVYN QPVYNQPVGA AGVPWMPAPQ PPLNCPPGLE YLSQIDQILI HQQIELLEVL TGFETNNKYE IKNSFGQRVY FAAEDTDCCT RNCCGPSRPF TLRIIDNMGQ EVITLERPLR CSSCCCPCCL QEIEIQAPPG VPIGYVIQTW HPCLPKFTIQ NEKREDVLKI SGPCVVCSCC GDVDFEIKSL DEQCVVGKIS KHWTGILREA FTDADNFGIQ FPLDLDVK
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: PLSCR1 phospholipid scramblase 1 [ Homo sapiens ]
Official Symbol: PLSCR1
Synonyms: PLSCR1; phospholipid scramblase 1; MMTRA1B; PL scramblase 1; erythrocyte phospholipid scramblase; ca(2+)-dependent phospholipid scramblase 1;
Gene ID: 5359
mRNA Refseq: NM_021105
Protein Refseq: NP_066928
MIM: 604170
UniProt ID: O15162
Chromosome Location: 3q23
Pathway: EGFR1 Signaling Pathway, organism-specific biosystem;
Function: CD4 receptor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; SH3 domain binding; calcium ion binding; calcium ion binding; enzyme bindin

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