Recombinant Human armadillo repeat containing 10, His-tagged

• Cat.No.: ARMC10-569H
• Product Overview: ARMC10, 28-308aa, Human, His tag, E.coli

Specification

• Description: AMRC10 is a protein that contains an armadillorepeat and transmembrane domain. The protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Recombinant human AMRC10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 33.6kDa (304aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSTRGRRRG DRELGIRSSK SAEDLTDGSY DDVLNAEQLQ KLLYLLESTE DPVIIERALI TLGNNAAFSV NQAIIRELGG IPIVANKINH SNQSIKEKAL NALNNLSVNV ENQIKIKIYI SQVCEDVFSG PLNSAVQLAG LTLLTNMTVT NDHQHMLHSY ITDLFQVLLT GNGNTKVQVL KLLLNLSENP AMTEGLLRAQ VDSSFLSLYD SHVAKEILLR VLTLFQNIKN CLKIEGHLAV QPTFTEGSLF FLLHGEECAQ KIRALVDHHD AEVKEKVVTI IPKI
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ARMC10 armadillo repeat containing 10 [ Homo sapiens ]
• Official Symbol: ARMC10
• Synonyms: ARMC10; armadillo repeat containing 10; armadillo repeat-containing protein 10; MGC3195; specific Splicing Variant involved in Hepatocarcinogenesis; SVH; splicing variant involved in hepatocarcinogenesis protein; specific splicing variant involved in hepatocarcinogenesis; PNAS112; PNAS-112; PSEC0198; FLJ37850
• Gene ID: 83787
• mRNA Refseq: NM_001161009
• Protein Refseq: NP_001154481
• MIM: 611864
• UniProt ID: Q8N2F6
• Chromosome Location: 7q22.1
• Function: binding