"KLF12" Related Products

Recombinant Human Kruppel-like factor 12, His-tagged

Cat.No.: KLF12-602H
Product Overview: KLF12, 1-402aa, Human, His tag, E.coli
Description: KLF12, as known as Krueppel-like factor 12, is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.cers. Recombinant human KLF12 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
Molecular Mass: 46.6 kDa(425aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMNIHMKR KTIKNINTFE NRMLMLDGMP AVRVKTELLE SEQGSPNVHN YPDMEAVPLL LNNVKGEPPE DSLSVDHFQT QTEPVDLSIN KARTSPTAVS SSPVSMTASA SSPSSTSTSS SSSSRLASSP TVITSVSSAS SSSTVLTPGP LVASASGVGG QQFLHIIHPV PPSSPMNLQS NKLSHVHRIP VVVQSVPVVY TAVRSPGNVN NTIVVPLLED GRGHGKAQMD PRGLSPRQSK SDSDDDDLPN VTLDSVNETG STALSIARAV QEVHPSPVSR VRGNRMNNQK FPCSISPFSI ESTRRQRRSE SPDSRKRRIH RCDFEGCNKV YTKSSHLKAH RRTHTGEKPY KCTWEGCTWK FARSDELTRH YRKHTGVKPF KCADCDRSFS RSDHLALHRR RHMLV
Purity: >85% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5mg/ml (determined by Bradford assay)
Gene Name: KLF12 Kruppel-like factor 12 [ Homo sapiens ]
Official Symbol: KLF12
Synonyms: KLF12; Kruppel-like factor 12; Krueppel-like factor 12; AP 2 repressor; AP 2rep; AP 2rep transcription factor; AP2REP; HSPC122; KLF12 zinc finger transcriptional repressor; AP-2 repressor; AP-2rep transcription factor; transcriptional repressor AP-2rep; AP-2rep;
Gene ID: 11278
mRNA Refseq: NM_007249
Protein Refseq: NP_009180
MIM: 607531
UniProt ID: Q9Y4X4
Chromosome Location: 13q22
Function: DNA binding; metal ion binding; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; zinc ion binding;

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