Recombinant Human polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa, His-tagged
Cat.No. : | POLR2K-669H |
Product Overview : | POLR2K, 1-58aa Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | POLR2K is one of the smallest subunits of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases. Recombinant human POLR2K protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT |
Molecular Mass : | 9.4 kDa (81aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMDTQKDV QPPKQQPMIY ICGECHTENE IKSRDPIRCR ECGYRIMYKK RTKRLVVFDA R |
Purity : | >85 % by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | POLR2K?polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa [?Homo sapiens?(human) ] |
Official Symbol : | POLR2K |
Synonyms : | POLR2K; RPB12; RPABC4; RPB7.0; hRPB7.0; hsRPB10a; RPB10alpha; ABC10-alpha; polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa; DNA-directed RNA polymerases I, II, and III subunit RPABC4; RNA polymerase II 7.0 kDa subunit; DNA-directed RNA polymerase II subunit K; RNA polymerases I, II, and III subunit ABC4; DNA directed RNA polymerases I, II, and III 7.0 kda polypeptide; NP_005025.1; EC 2.7.7.6 |
Gene ID : | 5440 |
mRNA Refseq : | NM_005034 |
Protein Refseq : | NP_005025 |
MIM : | 606033 |
UniProt ID : | P53803 |
Chromosome Location : | 8q22.2 |
Pathway : | Abortive elongation of HIV-1 transcript in the absence of Tat; Cytosolic DNA-sensing pathway; DNA Repair |
Function : | DNA binding; contributes_to RNA polymerase I activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
Polr2k-5001M | Recombinant Mouse Polr2k Protein, Myc/DDK-tagged | +Inquiry |
POLR2K-8510H | Active Recombinant Human POLR2K, GST-tagged | +Inquiry |
POLR2K-7846Z | Recombinant Zebrafish POLR2K | +Inquiry |
◆ Lysates | ||
POLR2K-3028HCL | Recombinant Human POLR2K 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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