Recombinant Canine CD40LG, Fc-tagged
Cat.No. : | CD40LG-167C |
Product Overview : | A DNA sequence encoding the canine CD40LG (O97626) (Met112-Leu260) was expressed with the Fc region of mouse IgG1 at the N-terminus. |
- Specification
- Gene Information
- Related Products
Source : | Human Cells |
Species : | Canine |
Tag : | Fc |
Form : | Lyophilized from sterile PBS, pH7.4. |
Molecular Mass : | The recombinant canine CD40LG is a disulfide-linked homodimer. The reduced monomer comprises 385 amino acids and has a predicted molecular mass of 42.5 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions. |
Protein length : | Met112-Leu260 |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >85 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70℃ |
Storage : | Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | CD40LG CD40 ligand [ Canis lupus familiaris ] |
Official Symbol : | CD40LG |
Synonyms : | CD40LG; CD40 ligand; CD40-L; tumor necrosis factor ligand superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome); CD154; TNFSF5; |
Gene ID : | 403468 |
mRNA Refseq : | NM_001002981 |
Protein Refseq : | NP_001002981 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; |
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◆ Lysates | ||
CD40LG-1080CCL | Recombinant Cynomolgus CD40LG cell lysate | +Inquiry |
CD40LG-001CCL | Recombinant Canine CD40LG cell lysate | +Inquiry |
CD40LG-1965HCL | Recombinant Human CD40LG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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- Reviews
Q&As (5)
Ask a questionYes, there are clinical trials investigating the modulation of CD40LG in autoimmune diseases, exploring its potential role in regulating immune responses that contribute to autoimmunity.
Yes, research suggests that CD40LG modulation might be a viable strategy in the development of treatments for infectious diseases by enhancing immune responses.
The interaction between CD40LG and CD40 is crucial for the activation of B cells, leading to the production of antibodies and the development of an effective immune response.
CD40LG is involved in modulating inflammatory responses by influencing the activation and function of immune cells, contributing to the regulation of the immune system.
CD40LG is being investigated as an adjuvant in vaccine development, aiming to enhance the immune response and improve the efficacy of vaccines against various diseases.
Customer Reviews (3)
Write a reviewThe reliable performance of the CD40LG protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.
Its reliable and accurate performance ensures dependable results, contributing to the advancement of scientific knowledge in various fields of study.
Their knowledgeable and responsive team assists in troubleshooting and finding solutions to any experimental challenges that may arise.
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