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Recombinant Canine CD40LG, Fc-tagged

Cat.No. : CD40LG-167C
Product Overview : A DNA sequence encoding the canine CD40LG (O97626) (Met112-Leu260) was expressed with the Fc region of mouse IgG1 at the N-terminus.
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  • Gene Information
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Source : Human Cells
Species : Canine
Tag : Fc
Form : Lyophilized from sterile PBS, pH7.4.
Molecular Mass : The recombinant canine CD40LG is a disulfide-linked homodimer. The reduced monomer comprises 385 amino acids and has a predicted molecular mass of 42.5 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions.
Protein length : Met112-Leu260
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >85 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70℃
Storage : Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : CD40LG CD40 ligand [ Canis lupus familiaris ]
Official Symbol : CD40LG
Synonyms : CD40LG; CD40 ligand; CD40-L; tumor necrosis factor ligand superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome); CD154; TNFSF5;
Gene ID : 403468
mRNA Refseq : NM_001002981
Protein Refseq : NP_001002981
Pathway : Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any ongoing clinical trials targeting CD40LG for autoimmune diseases? 11/01/2022

Yes, there are clinical trials investigating the modulation of CD40LG in autoimmune diseases, exploring its potential role in regulating immune responses that contribute to autoimmunity.

Can CD40LG be a potential target for the treatment of infectious diseases? 02/27/2021

Yes, research suggests that CD40LG modulation might be a viable strategy in the development of treatments for infectious diseases by enhancing immune responses.

How does the interaction between CD40LG and its receptor CD40 influence antibody production? 11/20/2020

The interaction between CD40LG and CD40 is crucial for the activation of B cells, leading to the production of antibodies and the development of an effective immune response.

How is CD40LG involved in the regulation of inflammatory responses? 08/26/2020

CD40LG is involved in modulating inflammatory responses by influencing the activation and function of immune cells, contributing to the regulation of the immune system.

In what ways is CD40LG being explored for its potential in vaccine development? 04/20/2020

CD40LG is being investigated as an adjuvant in vaccine development, aiming to enhance the immune response and improve the efficacy of vaccines against various diseases.

Customer Reviews (3)

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Reviews
10/17/2022

    The reliable performance of the CD40LG protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.

    01/01/2022

      Its reliable and accurate performance ensures dependable results, contributing to the advancement of scientific knowledge in various fields of study.

      11/16/2020

        Their knowledgeable and responsive team assists in troubleshooting and finding solutions to any experimental challenges that may arise.

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