Recombinant Canine NRG1 NRG1-178C

Recombinant Canine NRG1

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Recombinant Canine NRG1

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Cat.No. : NRG1-178C
Product Overview : A DNA sequence encoding the canine NRG1 isoform alpha (XP_858147.1) extracellular domain (Ser19-Lys240) was expressed with five amino acids (DDDDK) at the C- terminus.
Source : Human Cells
Species : Canine
Form : Lyophilized from sterile PBS, pH7.4.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized canine NRG1 at 10 μg/ml (100 μl/well) can bind human ErbB4-Fc, The EC50 of human ErbB4-Fc is 0.19-0.43 μg/ml.
Molecular Mass : The recombinant canine NRG1 comprises 228 amino acids and has a predicted molecular mass of 24.7 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Protein length : Ser19-Lys240
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >95 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70℃
Storage : Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : NRG1 neuregulin 1 [ Canis lupus familiaris ]
Official Symbol : NRG1
Synonyms : NRG1; neuregulin 1; pro-neuregulin-1, membrane-bound isoform;
Gene ID : 482861
Pathway : ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem;

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