Recombinant Canine NRG1


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Recombinant Canine NRG1

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Cat.No. : NRG1-178C
Product Overview : A DNA sequence encoding the canine NRG1 isoform alpha (XP_858147.1) extracellular domain (Ser19-Lys240) was expressed with five amino acids (DDDDK) at the C- terminus.
Source : Human Cells
Species : Canine
Form : Lyophilized from sterile PBS, pH7.4.
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized canine NRG1 at 10 μg/ml (100 μl/well) can bind human ErbB4-Fc, The EC50 of human ErbB4-Fc is 0.19-0.43 μg/ml.
Molecular Mass : The recombinant canine NRG1 comprises 228 amino acids and has a predicted molecular mass of 24.7 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Protein length : Ser19-Lys240
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >95 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70℃
Storage : Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : NRG1 neuregulin 1 [ Canis lupus familiaris ]
Official Symbol : NRG1
Synonyms : NRG1; neuregulin 1; pro-neuregulin-1, membrane-bound isoform;
Gene ID : 482861
Pathway : ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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