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Recombinant Human PRNP, Fc-tagged

Cat.No.: PRNP-373H
Product Overview: A DNA sequence encoding the human PRNP (NP_000302.1) (Met1-Gly229) was expressed with the Fc region of human IgG1 at the C-terminus.
Source: Human Cells
Species: Human
Tag: Fc
Form: Lyophilized from sterile PBS, pH7.4.
Molecular Mass: The recombinant human PRNP/Fc comprises 448 amino acids and has a predicted molecular mass of 49.7 kDa. The apparent molecular mass of the protein is approximately 57.4 kDa in SDS-PAGE under reducing conditions.
Protein length: Met1-Gly229
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: >90 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name: PRNP prion protein [ Homo sapiens ]
Official Symbol: PRNP
Synonyms: PRNP; prion protein; CJD, GSS, prion protein (p27 30) , PRIP; major prion protein; CD230; Creutzfeldt Jakob disease; fatal familial insomnia; Gerstmann Strausler Scheinker syndrome; p27 30; PRP; CD230 antigen; prion-related protein; CJD; GSS; PrP; ASCR; PRIP; PrPc; p27-30; PrP27-30; PrP33-35C; MGC26679;
Gene ID: 5621
mRNA Refseq: NM_000311
Protein Refseq: NP_000302
MIM: 176640
UniProt ID: P04156
Chromosome Location: 20p13
Pathway: Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Glypican 1 network, organism-specific biosystem; NCAM signaling for neurite out-growth, organism-specific biosystem; NCAM1 interactions, organism-specific biosystem; Prion diseases, organism-specific biosystem; Prion diseases, conserved biosystem;
Function: ATP-dependent protein binding; chaperone binding; copper ion binding; copper ion binding; identical protein binding; metal ion binding; microtubule binding; protein binding; tubulin binding;

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