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Recombinant Rat Arpc5l, His-tagged

Cat.No. : Arpc5l-3107R
Product Overview : Actin-related protein 2/3 complex subunit 5-like protein (Arpc5l)
  • Specification
  • Gene Information
  • Related Products
Source : E. Coli or Yeast
Species : Rat
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 153
Purity : >90%
Notes : Small volumes of Arpc5l recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : Arpc5l actin related protein 2/3 complex, subunit 5-like [ Rattus norvegicus ]
Official Symbol : Arpc5l
Synonyms : Arpc5l; actin-related protein 2/3 complex subunit 5-like protein; ARC16-2; arp2/3 complex 16 kDa subunit 2
Gene ID : 296710
mRNA Refseq : NM_001037767
Protein Refseq : NP_001032856
UniProt ID : A1L108
Chromosome Location : 3q11
Pathway : Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem
Function : actin binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Is ARPC5L protein ubiquitously expressed in all cell types? 10/19/2021

ARPC5L expression has been observed in a wide range of tissues and cell types, suggesting it is likely expressed ubiquitously. Nonetheless, its expression levels may vary depending on the cell type or tissue and can be regulated in a context-specific manner.

Can ARPC5L depletion or disruption result in cellular abnormalities? 09/29/2020

Yes, ARPC5L depletion or disruption can lead to cellular abnormalities. Impaired actin cytoskeleton regulation, caused by ARPC5L dysfunction, can affect various cellular processes such as cell shape, migration, and division.

Does ARPC5L have any role in neuronal development or synaptic plasticity? 11/22/2019

There is evidence suggesting that ARPC5L is involved in neuronal development and synaptic plasticity. It participates in the formation of dendritic spines, which are essential for synaptic connections and neuronal communication.

Are there any known drugs that target ARPC5L or the ARP2/3 complex? 09/25/2019

Currently, there are no specific drugs available that directly target ARPC5L or the ARP2/3 complex. However, various small molecules and compounds that indirectly modulate actin dynamics are under investigation for their potential in therapeutics targeting Actin-related processes.

Are there any known interacting proteins or complexes with ARPC5L? 12/26/2016

ARPC5L interacts with various proteins and complexes involved in actin dynamics and cell signaling. Some of the known interacting partners include other subunits of the ARP2/3 complex, actin-binding proteins, signaling molecules like Rho GTPases, and adaptor proteins involved in membrane trafficking.

Is ARPC5L involved in cytokinesis? 12/20/2016

Yes, ARPC5L plays a role in cytokinesis, the process of cell division. It helps in the formation of the actin-based contractile ring, which drives the separation of daughter cells during cytokinesis.

Are there any known genetic disorders associated with ARPC5L mutations? 07/05/2016

Currently, there are no known specific genetic disorders directly attributed to ARPC5L mutations. However, abnormalities in actin cytoskeleton regulation, which ARPC5L is involved in, can contribute to various developmental and disease-related phenotypes.

Customer Reviews (3)

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Reviews
07/18/2021

    The manufacturer's commitment to delivering a high-quality product further enhances its reputation and guarantees its suitability for a wide range of research applications.

    06/25/2021

      In addition to its outstanding quality, the manufacturer of the ARPC5L protein provides excellent technical support, which is a valuable asset for researchers

      01/13/2021

        The ARPC5L protein is of exceptional quality, making it an ideal choice to meet my experimental requirements.

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