Recombinant Rat Akr1b1, His-tagged
Cat.No. : | Akr1b1-3269R |
Product Overview : | Aldose reductase (Akr1b1) |
- Specification
- Gene Information
- Related Products
Description : | regulates NF-kappa B mediated mitogenic signaling; may play a role in the polyol pathway . |
Source : | E. Coli or Yeast |
Species : | Rat |
Tag : | His |
Form : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Protein length : | 316 |
Purity : | >90% |
Notes : | Small volumes of Akr1b1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Store at -20 degree C. For extended storage, store at -20 or -80 degree C. |
Storage Buffer : | PBS pH 7.4, 50% glycerol |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | Akr1b1 aldo-keto reductase family 1, member B1 (aldose reductase) [ Rattus norvegicus ] |
Official Symbol : | Akr1b1 |
Synonyms : | AKR1B1; aldo-keto reductase family 1, member B1 (aldose reductase); |
Gene ID : | 116586 |
Products Types
◆ Recombinant Protein | ||
AKR1B1-120R | Recombinant Rhesus Macaque AKR1B1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AKR1B1-252R | Recombinant Rat AKR1B1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AKR1B1-9156H | Active Recombinant Human AKR1B1, His-tagged | +Inquiry |
AKR1B1-2656H | Recombinant Human AKR1B1 protein(11-290 aa), C-His-tagged | +Inquiry |
AKR1B1-304H | Recombinant Human AKR1B1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
AKR1B1-47HCL | Recombinant Human AKR1B1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (15)
Ask a questionAKR1B1 is associated with the proliferation, invasion and metastasis of some human tumors as well as the occurrence and development of drug resistance, so it has a certain importance in tumor therapy.
AKR1B1 inhibitors can be used in the treatment of related diseases such as diabetes and retinopathy, as well as in drug development for diseases such as cancer and malaria.
AKR1B1 gene mutation is associated with the occurrence and development of certain diseases, such as diabetes, lung cancer and so on.
The detection methods of AKR1B1 protein include fluorescence immunoassay, gas chromatography-mass spectrometry, transmission electron microscopy and other methods.
AKR1B1 is involved in glucose oxidative metabolism and neuronal survival in nervous system diseases, and can be used as a target for drug treatment of diabetic neuropathy and central nervous system diseases.
AKR1B1 protein is involved in lymphocyte differentiation, cell proliferation and movement in the immune system, which can affect the immune response of the body.
The AKR1B1 protein (also known as aldose reductase) is a REDOX reductase belonging to the sterol adenylate superfamily, which is capable of reducing aldehydes and alpha-beta ketones and is found in many cell types such as the eye, nervous system, kidney, bone and vascular tissue.
AKR1B1 protein has been implicated in a variety of diseases, such as diabetes, cancer, retinopathy, and neurological diseases.
AKR1B1 protein is widely expressed in various organs and cells of the human body, such as retina, nervous system, kidney, blood vessels, heart and so on.
AKR1B1 protein is commonly seen in advanced retinopathy in patients with diabetes and is associated with the development and further deterioration of this disease.
The expression level of AKR1B1 protein is up-regulated in a variety of benign and malignant motor neuron diseases, such as ALS and amyotrophic lateral sclerosis.
AKR1B1 is mainly involved in hexaosaccharide metabolism, catalyzing the conversion of glucose and aldehyde condensates to produce alcohol condensates, maintaining the balance of intracellular glucose metabolism and reducing oxidative damage to cells.
The abnormal expression of AKR1B1 protein is associated with a variety of disorders of glucose metabolism, such as diabetes mellitus and polycystic ovary syndrome.
AKR1B1 protein is commonly found in neurological diseases and is associated with the occurrence and development of neurodegenerative diseases.
AKR1B1 protein is closely related to the occurrence and development of diabetes, and can be used as an adjuvant drug target for diabetes, which has certain clinical application value.
Customer Reviews (4)
Write a reviewCan induce specific immune responses in immunotherapy, which has potential value for the treatment of diseases.
Good application potential in protein engineering and recombinant expression.
AKR1B1 can induce immune protective effect and has potential for disease prevention.
Effective in drug delivery systems for drug loading and release.
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