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Recombinant Mouse Adra1d, His-tagged

Cat.No. : Adra1d-3318M
Product Overview : Alpha-1D adrenergic receptor (Adra1d)
  • Specification
  • Gene Information
  • Related Products
Source : E. Coli or Yeast
Species : Mouse
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 562
Purity : >90%
Notes : Small volumes of Adra1d recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : Adra1d adrenergic receptor, alpha 1d [ Mus musculus ]
Official Symbol : Adra1d
Synonyms : Spr8; Adra1; Gpcr8; [a]1d; Adra-1; Adra1a; alpha1D-AR; alpha-1D adrenergic receptor; alpha-1D adrenoceptor; alpha-1D adrenoreceptor; alpha-1A adrenergic receptor
Gene ID : 11550
mRNA Refseq : NM_013460
Protein Refseq : NP_038488
Chromosome Location : 2 F1; 2 63.5 cM
Pathway : Adrenergic signaling in cardiomyocytes, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem
Function : G-protein coupled receptor activity; adrenergic receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (17)

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How is the ADRA1D receptor related to hypertension? 11/23/2022

The ADRA1D receptor plays a role in regulating the constriction of blood vessels, which affects blood pressure. Dysfunction of the ADRA1D receptor may contribute to the development of hypertension (high blood pressure).

How can knowledge about the ADRA1D protein contribute to advancements in medicine? 08/29/2022

Understanding the function of the ADRA1D protein and its role in different medical conditions can allow researchers to develop more targeted and effective treatments. Additionally, identifying potential genetic mutations in the ADRA1D gene can help with the diagnosis and treatment of certain disorders.

Can drugs that target the ADRA1D protein interact with other medications? 01/19/2022

Yes, drugs that target the ADRA1D protein can interact with other medications, including other blood pressure medications, antidepressants, and medications used to treat erectile dysfunction.

What are the potential side effects of drugs that target the ADRA1D protein? 12/10/2021

Side effects of drugs that target the ADRA1D protein may include dizziness, headaches, fatigue, nausea, and abdominal pain. More serious side effects can include low blood pressure, palpitations, and difficulty breathing.

Can genetic mutations in the ADRA1D gene affect its function? 05/07/2021

Yes, genetic mutations in the ADRA1D gene can affect the function of the ADRA1D protein, potentially leading to altered vasoconstriction, urinary tract function, and neurotransmitter release.

Are there any known mutations in the ADRA1D gene that cause disease? 08/19/2020

There are no known mutations in the ADRA1D gene that cause disease, but certain genetic variations in this gene may be associated with an increased risk of certain conditions, such as hypertension.

In what forms are drugs that target the ADRA1D protein available? 05/30/2020

Drugs that target the ADRA1D protein are typically available in oral tablets or capsules. They can also be administered as injections in a medical setting.

Is there ongoing research on the ADRA1D protein? 11/10/2019

Yes, there is ongoing research on the ADRA1D protein and its potential role in various medical conditions. Researchers are also exploring new drug targets and treatments that target the ADRA1D protein.

What medical conditions are associated with dysfunction of the ADRA1D receptor? 06/29/2019

Dysfunction of the ADRA1D receptor may be associated with various medical conditions, including hypertension, lower urinary tract symptoms, benign prostatic hyperplasia, and depression.

What medical conditions are associated with the ADRA1D protein? 06/16/2019

The ADRA1D protein has been implicated in the development of several medical conditions, including hypertension, urinary incontinence, and neurological disorders such as schizophrenia and bipolar disorder.

Are there any natural substances that target the ADRA1D receptor? 03/21/2019

Yes, certain natural substances have been found to target the ADRA1D receptor, including elderflower extract and apigenin, a flavonoid found in fruits and vegetables.

Can targeting the ADRA1D receptor be a potential therapeutic strategy for certain medical conditions? 01/10/2019

Yes, targeting the ADRA1D receptor can be a potential therapeutic strategy for certain medical conditions, such as hypertension, lower urinary tract symptoms, and depression. However, further research is needed to fully understand its role and potential therapeutic applications.

Are there any drugs that target the ADRA1D receptor? 06/15/2018

Yes, there are drugs that target the ADRA1D receptor, including selective alpha-1 adrenergic receptor antagonists (such as prazosin) and alpha-1 adrenergic agonists (such as phenylephrine).

Is the ADRA1D receptor involved in the development of neurodegenerative diseases? 04/07/2017

There is some evidence that the ADRA1D receptor may be involved in the development of neurodegenerative diseases, such as Alzheimer's disease. However, further research is needed to fully understand its role in these conditions.

Is it safe to use drugs that target the ADRA1D protein during pregnancy or breastfeeding? 06/14/2016

The use of drugs that target the ADRA1D protein during pregnancy or breastfeeding has not been extensively studied and should be used with caution. Pregnant or breastfeeding individuals should consult with their healthcare provider before using these medications.

Are there any drugs that target the ADRA1D protein? 01/26/2016

Yes, several drugs that target the ADRA1D protein have been developed, including prazosin and doxazosin, which are commonly used to treat high blood pressure.

How is the ADRA1D receptor related to lower urinary tract symptoms? 01/18/2016

The ADRA1D receptor is expressed in the smooth muscle cells of the bladder and urethra, and its activation causes relaxation of these muscles. Dysfunction of the ADRA1D receptor may contribute to lower urinary tract symptoms, such as difficulty in urination and urinary incontinence.

Customer Reviews (5)

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Reviews
02/16/2021

    Thanks to the excellent technical support provided by the manufacturer, any queries or concerns I had were promptly resolved, making the entire process seamless and hassle-free.

    07/17/2020

      The ADRA1D protein provided by the manufacturer is of exceptional quality and meets all of my experimental requirements with high specificity and activity.

      06/23/2020

        I also appreciate the detailed protocols and technical information provided by the manufacturer, which have been a valuable resource throughout my project.

        08/21/2019

          the purity and stability of the protein are unparalleled, ensuring reproducible experimental results every time.

          04/07/2018

            I am extremely satisfied with my experience with this product and the manufacturer's outstanding support team, and I highly recommend their products and services.

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