Recombinant Human GNA11, GST-tagged
Cat.No. : | GNA11-22H |
Product Overview : | Recombinant Human GNA11(1 a.a. - 359 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 68.5 kDa |
AA Sequence : | MTLESMMACCLSDEVKESKRINAEI EKQLRRDKRDARRELKLLLLGTGES GKSTFIKQMRIIHGAGYSEEDKRGF TKLVYQNIFTAMQAMIRAMETLKIL YKYEQNKANALLIREVDVEKVTTFE HQYVSAIKTLWEDPGIQECYDRRRE YQLSDSAKYYLTDVDRIATLGYLPT QQDVLRVRVPTTGIIEYPFDLENII FRMVDVGGQRSERRKWIHCFENVTS IMFLVALSEYDQVLVESDNENRMEE SKALFRTIITYPWFQNSSVILFLNK KDLLEDKILYSHLVDYFPEFDGPQR DAQAAREFILKMFVDLNPDSDKIIY SHFTCATDTENIRFVFAAVKDTILQ LNLKEYNLV |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) [ Homo sapiens (human) ] |
Official Symbol : | GNA11 |
Synonyms : | GNA11; FBH; FBH2; FHH2; HHC2; GNA-11; HYPOC2; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); guanine nucleotide-binding protein subunit alpha-11; g alpha-11; G-protein subunit alpha-11; guanine nucleotide-binding protein G(y) subunit alpha |
Gene ID : | 2767 |
mRNA Refseq : | NM_002067 |
Protein Refseq : | NP_002058 |
MIM : | 139313 |
UniProt ID : | P29992 |
Chromosome Location : | 19p13.3 |
Pathway : | ADP signalling through P2Y purinoceptor 1; Calcium Regulation in the Cardiac Cell; Cholinergic synapse |
Function : | G-protein beta/gamma-subunit complex binding; G-protein coupled receptor binding; GTP binding |
Products Types
◆ Recombinant Protein | ||
GNA11-995H | Recombinant Human GNA11 Protein, His (Fc)-Avi-tagged | +Inquiry |
Gna11-3253M | Recombinant Mouse Gna11 Protein, Myc/DDK-tagged | +Inquiry |
GNA11-3752M | Recombinant Mouse GNA11 Protein, His (Fc)-Avi-tagged | +Inquiry |
GNA11-1709R | Recombinant Rhesus Macaque GNA11 Protein, His (Fc)-Avi-tagged | +Inquiry |
GNA11-2245R | Recombinant Rat GNA11 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GNA11-5872HCL | Recombinant Human GNA11 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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