||Canine CCL2/MCP-1 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
||Chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemotactic protein-1 (MCP-1), is a small cytokine belonging to the CC chemokine family. There are at least 27 distinct members of the C-C subgroup reported for mammals. They are characterized by two adjacent cysteines. CCL2 (MCP-1) recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. CCL2 (MCP-1) is implicated in pathogeneses of several diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis and atherosclerosis.
||QPDAIISPVT CCYTLTNKKI SIQRLASYKR VTSSKCPKEA VIFKTVLNKE ICADPKQKWV QDSMAHLDKK SQTQTAKP (78)
||The Canine CCL2/MCP-1 protein can be used in cell culture, as an CCL2/MCP-1 ELISA Standard, and as a Western Blot Control.