Recombinant Ovine CXCL10 (IP-10)
Cat.No. : | CXCL10-50O |
Product Overview : | Ovine CXCL10/IP-10 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
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Description : | C-X-C motif chemokine 10 (CXCL10) also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 is a member of the C-X-C chemokine family. CXCL10 (IP-10) is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. There have been 17 different C-X-C chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes. CXCL10 (IP-10) elicits its effects by binding to the cell surface chemokine receptor CXCR3. |
Source : | Yeast |
Species : | Ovine |
Form : | Lyophilized |
Molecular Mass : | 9.4 kDa |
AA Sequence : | IPLSRNTRCT CIEISNGSVN PRSLEKLELI PASQSCPRVE IIATMKRNGE KRCLNPESKT IKNLLKAINK QRTKRSPRTQ KEA (83) |
Applications : | The Ovine CXCL10/IP-10 protein can be used in cell culture, as an CXCL10/IP-10 ELISA Standard, and as a Western Blot Control. |
Storage : | -20 C |
Products Types
◆ Recombinant Protein | ||
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CXCL10-050H | Recombinant Human CXCL10 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CXCL10-4341D | Recombinant Dolphin CXCL10 Protein | +Inquiry |
Cxcl10-2774H | Recombinant Hamster Cxcl10 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CXCL10-7172HCL | Recombinant Human CXCL10 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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