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Specification Related Products

Cat.No. :	Csf2-94C
Description :	Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Granulocyte macrophage–colony stimulating factor (GM-CSF) is secreted in response to inflammatory stimuli such as LPS, IL-1, and TNF-α by a variety of different cells, including endothelium, fibroblasts, muscle cells, and macrophages, and by activated T cells. GM-CSF is glycosylated in its mature form.
Source :	Yeast
Species :	Canine
Form :	Lyophilized
Bio-activity :	The biological activity of recombinant canine GM-CSF was measured in a cell proliferation assay using the human TF-1 cell line. The ED50 for this effect is typically 25 - 45 ng/mL.
Molecular Mass :	14.2 kDa
AA Sequence :	APTRSPTLVT RPSQHVDAIQ EALSLLNNSN DVTAVMNKAV KVVSEVFDPE GPTCLETRLQ LYKEGLQGSL TSLKNPLTMM ANHYKQHCPP TPESPCATQN INFKSFKENL KDFLFNIPFD CWKPVKK (127)
Applications :	The GM-CSF protein can be used in cell culture, as a GM-CSF ELISA Standard, and as a Western Blot Control.
Storage :	-20 C