Active Recombinant Guinea Pig Il8

• Cat.No.: Il8-307P
• Product Overview: Guinea Pig IL-8 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.

Specification

• Description: Interleukin-8 (IL-8), also known as CXCL8, is a CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. There have been 17 different CXC chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the CXC motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2.
• Source: Yeast
• Species: Guinea Pig
• Form: Lyophilized
• Bio-activity: In testing
• Molecular Mass: Guinea Pig IL-8 has a predicted molecular weight of 9.1 kDa.
• AA Sequence: MVVTKLVSEL RCQCIKIHTT PFHPKFIKEL KVIESGPRCA NSEIIVKLSD NRQLCLDPKK KWVQDVVSMF LKRTESQDS (79)
• Purity: >95% as visualized by SDS-PAGE analysis.
• Applications: The Guinea Pig IL-8 protein can be used in cell culture, as an IL-8 ELISA Standard, and as a Western Blot Control.
• Storage: Stable for up to twelve months from date of receipt at -20?C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20?C. Avoid repeated freeze/thaw cycles.
• Reconstitution: Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

Gene Information

• Gene Name: Il8 interleukin 8 [ Cavia porcellus (domestic guinea pig) ]
• Official Symbol: Il8
• Synonyms: Il8; IL-8; CXCL8; NAP-1; interleukin 8; interleukin-8; C-X-C motif chemokine 8; Neutrophil attractant protein 1; neutrophil attractant protein-1
• Gene ID: 100379599
• mRNA Refseq: NM_001173399
• Protein Refseq: NP_001166870
• UniProt ID: P49113
• Chromosome Location: Un