"TIMP3" Related Products


Recombinant Human TIMP3 protein, Fc-tagged

Cat.No.: TIMP3-002H
Product Overview: Recombinant Human TIMP3(Cys24-Pro211) fused with Fc region of human IgG1 at N-terminal was expressed in HEK293.
Source: HEK293
Species: Human
Tag: Fc
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to induce alkaline phosphatase production.
Molecular Mass: The predicted molecular mass is 48 kDa, and the apparent molecular mass is approximately 55 kDa in SDS-PAGE under reducing conditions.
Protein length: Cys24-Pro211
Endotoxin: <0.06 EU/μg as determined by LAL test.
Purity: >95%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade. Avoid freeze/thaw cycles.
Reconstitution: Reconstitute with sterile water to a concentration of 1mg/ml. Add 1xPBS to the desired protein concentration.
Gene Name: TIMP3 TIMP metallopeptidase inhibitor 3 [ Homo sapiens ]
Official Symbol: TIMP3
Synonyms: TIMP3; TIMP metallopeptidase inhibitor 3; SFD, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory); metalloproteinase inhibitor 3; TIMP-3; MIG-5 protein; protein MIG-5; tissue inhibitor of metalloproteinases 3; SFD; K222; K222TA2; HSMRK222;
Gene ID: 7078
mRNA Refseq: NM_000362
Protein Refseq: NP_000353
MIM: 188826
UniProt ID: P35625
Chromosome Location: 22q12.3
Pathway: Endochondral Ossification, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem;
Function: enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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