Active Recombinant Human CXCL6, MIgG2a Fc-tagged

• Cat.No.: CXCL6-123H
• Product Overview: The extracellular domain of human CXCL6 (AAH13744.1)(Val40-Asn114) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.

Specification

• Source: CHO cell
• Species: Human
• Tag: MIgG2a Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to induce myeloperoxidase.
• Molecular Mass: 34KDa (monomer)
• AA Sequence: Val40-Asn114
• Endotoxin: <0.06 eu/μg as determined by lal test.>
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) [ Homo sapiens ]
• Official Symbol: CXCL6
• Synonyms: CXCL6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); SCYB6, small inducible cytokine subfamily B (Cys X Cys), member 6 (granulocyte chemotactic protein 2); C-X-C motif chemokine 6; CKA 3; GCP 2; chemokine alpha 3; small-inducible cytokine B6; granulocyte chemotactic protein 2; Small inducible cytokine subfamily B (Cys-X-Cys), member b; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2); GCP2; CKA-3; GCP-2; SCYB6
• Gene ID: 6372
• mRNA Refseq: NM_002993
• Protein Refseq: NP_002984
• MIM: 138965
• UniProt ID: P80162
• Chromosome Location: 4q13.3
• Pathway: Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem
• Function: chemokine activity; heparin binding