Recombinant Human Chemokine (C-X-C Motif) Ligand 10, HIgG1 Fc-tagged CXCL10-242H

Recombinant Human Chemokine (C-X-C Motif) Ligand 10, HIgG1 Fc-tagged

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Recombinant Human Chemokine (C-X-C Motif) Ligand 10, HIgG1 Fc-tagged

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Cat.No. : CXCL10-242H
Product Overview : The extracellular domain of human CXCL10 (AAH10954.1)(Val22-Pro98) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO celL
Description : This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.
Source : CHO cells
Species : Human
Tag : HIgG1 Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to chemoattract BaF3 mouse pro-B cells.
Molecular Mass : 35KDa (monomer)
AA Sequence : Val22-Pro98
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : CXCL10 chemokine (C-X-C motif) ligand 10 [ Homo sapiens ]
Official Symbol : CXCL10
Synonyms : CXCL10; chemokine (C-X-C motif) ligand 10; INP10, SCYB10, small inducible cytokine subfamily B (Cys X Cys), member 10; C-X-C motif chemokine 10; C7; crg 2; gIP 10; IFI10; IP 10; mob 1; gamma IP10; gamma-IP10; small-inducible cytokine B10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10;
Gene ID : 3627
mRNA Refseq : NM_001565
Protein Refseq : NP_001556
MIM : 147310
UniProt ID : P02778
Chromosome Location : 4q21
Pathway : CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function : cAMP-dependent protein kinase regulator activity; chemokine activity; receptor binding;

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