Recombinant Human BTLA, MIgG2a Fc-tagged BTLA-188H

Recombinant Human BTLA, MIgG2a Fc-tagged

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Recombinant Human BTLA, MIgG2a Fc-tagged

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Cat.No. : BTLA-188H
Product Overview : The extracellular domain of human CD272 (NP_861445.3) (Lys31-Ser157) is fused to the N-terminus of the Fc region of mouse IgG2awas expressed in CHO cell
Description : This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis
Source : CHO cells
Species : Human
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured in a competitive binding assay.
Molecular Mass : 41KDa (monomer)
AA Sequence : Lys31-Ser157
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : BTLA B and T lymphocyte associated [ Homo sapiens ]
Official Symbol : BTLA
Synonyms : BTLA; B and T lymphocyte associated; B- and T-lymphocyte attenuator; BTLA1; CD272; B and T lymphocyte attenuator; B- and T-lymphocyte-associated protein; FLJ16065; MGC129743;
Gene ID : 151888
mRNA Refseq : NM_001085357
Protein Refseq : NP_001078826
MIM : 607925
UniProt ID : Q7Z6A9
Chromosome Location : 3q13.2
Pathway : Adaptive Immune System, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem;
Function : receptor activity;

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