btla

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btla

Official Full Name B and T lymphocyte associated
Background This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
Synonyms BTLA; B and T lymphocyte associated; B- and T-lymphocyte attenuator; BTLA1; CD272; B and T lymphocyte attenuator; B- and T-lymphocyte-associated protein; FLJ16065; MGC129743
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus
    • Rhesus monkey
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • Avi
    • Fc
    • DDK
    • His
    • Fc Chimera
    • GST
    • hIgG1
    • hIgG4
    • T7
    • human
    • IgG1
    • Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BTLA-001H Recombinant Human BTLA Protein, His-tagged E.coli His
    Human BTLA-348H Recombinant Human BTLA protein, His-tagged HEK293 His
    Human BTLA-567H Recombinant Human BTLA Protein, Fc-Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human BTLA-568H Recombinant Human BTLA Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Rhesus BTLA-994R Recombinant Rhesus BTLA Protein (Met1-Leu155), His-tagged HEK293 His
    Human BTLA-017H Recombinant Human BTLA protein, DDK/HIS-tagged HEK293 DDK/His
    Human BTLA-018H Recombinant Human BTLA protein, DDK/HIS-tagged HEK293 DDK/His
    Human BTLA-188H Recombinant Human BTLA, MIgG2a Fc-tagged CHO Fc
    Human BTLA-189H Recombinant Human BTLA, HIgG1 Fc-tagged CHO Fc
    Human BTLA-190H Recombinant Human BTLA protein, His-tagged HEK293 His
    Human BTLA-191H Recombinant Human BTLA protein, Fc/His-tagged HEK293 Fc/His
    Human BTLA-192H Recombinant Human BTLA protein, Fc-tagged HEK293 human/IgG1/Fc
    Human BTLA-233H Recombinant Human BTLA protein, Fc-tagged HEK293 human/IgG1/Fc
    Human BTLA-27110TH Recombinant Human BTLA, His-tagged E.coli His
    Human BTLA-2828H Recombinant Human BTLA Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human BTLA-3037H Recombinant Human B and T Lymphocyte Associated, His-tagged E.coli His
    Human BTLA-389H Recombinant Human BTLA Protein, GST-tagged Wheat Germ GST
    Human BTLA-411H Recombinant Human BTLA, Fc Chimera NS0 Fc Chimera
    Human BTLA-565H Recombinant Human BTLA, Fc-tagged, Biotinylated Human Cell Fc
    Human BTLA-566H Recombinant Human BTLA Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
    Mouse BTLA-1278MCL Recombinant Mouse BTLA cell lysate Human Cell N/A
    Mouse Btla-1843M Recombinant Mouse Btla protein, His & T7-tagged E.coli His/T7
    Mouse BTLA-8698M Recombinant Mouse BTLA protein, Fc-tagged HEK293 human/IgG1/Fc
    Mouse BTLA-8699M Recombinant Mouse BTLA protein, His-tagged HEK293 His
    Rat BTLA-1032R Recombinant Rat BTLA Protein Mammalian Cell His
    Rat BTLA-1148R Recombinant Rat BTLA Protein, Fc-tagged HEK293 Fc
    Rat Btla-1844R Recombinant Rat Btla protein, His & T7-tagged E.coli His/T7
    Cynomolgus Monkey BTLA-195C Recombinant Cynomolgus BTLA, Fc-tagged Human Cell Fc
    Cynomolgus Monkey BTLA-732CCL Recombinant Cynomolgus BTLA cell lysate Human Cell N/A
    Rhesus monkey BTLA-1525R Recombinant Rhesus Monkey BTLA Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey BTLA-1526R Recombinant Rhesus Monkey BTLA Protein, hIgG4-tagged HEK293 hIgG4

    btla involved in several pathways and played different roles in them. We selected most pathways btla participated on our site, such as Adaptive Immune System, Costimulation by the CD28 family, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with btla were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System CD300LH; KLHL20; AP2B1; ASB4; CTLA4; FCGR1B; WSB1; AGO1; AGO3; LRSAM1
    Costimulation by the CD28 family MAP3K8; CTLA4; BTLA; THEM4; MAPKAP1; HLA-DQB2; PDPK1A; CSK
    Immune System CD300A; PJA1; KIR3DS1; ART1; RNF34; ASB10; ALCAMB; LRR1; SEC61B; KIF18A

    btla has several biochemical functions, for example, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by btla itself. We selected most functions btla had, and list some proteins which have the same functions with btla. You can find most of the proteins on our site.

    Function Related Protein
    receptor activity GFRA4A; LILRB3; AGER; PAQR3B; GRIK5; PAQR4; PAQR9; TNFRSF10B; RNF139; CHRM3

    btla has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with btla here. Most of them are supplied by our site. Hope this information will be useful for your research of btla.

    TNFRSF14; PTPN6; PTPN11

    Venner, JM; Famulski, KS; et al. Molecular Landscape of T Cell-Mediated Rejection in Human Kidney Transplants: Prominence of CTLA4 and PD Ligands. AMERICAN JOURNAL OF TRANSPLANTATION 14:2565-2576(2014).
    Uchiyama, M; Jin, X; et al. Combination of Anti-BTLA Antibody (6B2) and Anti-PD-1 Antibody (PIM-2) Induced Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allograft.. TRANSPLANTATION 98:311-311(2014).

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