Active Recombinant Mouse CD28, MIgG2a Fc-tagged

• Cat.No.: CD28-232M
• Product Overview: The extracellular domain of mouse CD28 (NP_031668.3) (Lys21-Lys149) is fused to the N-terminus of the Fc region of mouse IgG2a.

Specification

• Source: CHO cells
• Species: Mouse
• Tag: MIgG2a Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells.
• Molecular Mass: 41 KDa (monomer)
• AA Sequence: Lys21-Lys149
• Endotoxin: <0.06 eu/μg as determined by lal test.>
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Cd28 CD28 antigen [ Mus musculus ]
• Official Symbol: CD28
• Synonyms: CD28; CD28 antigen; T-cell-specific surface glycoprotein CD28
• Gene ID: 12487
• mRNA Refseq: NM_007642
• Protein Refseq: NP_031668
• Pathway: Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem
• Function: SH3/SH2 adaptor activity; protease binding; protein homodimerization activity