||Recombinant Human Cytochrome P450 4F2 isozyme microsomes, with P450 Reductase and cytochrome b5 was expressed in baculovirus infected insect cells.
||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away.
||baculovirus infected insect cells
||Solution in 100 mM potassium phosphate buffer, pH 7.4.
||The CYP4F2 isoform catalyzes the 20-hydroxylation of leukotriene B4.