Active Recombinant Human CYP4F2

• Cat.No.: CYP4F2-555H
• Product Overview: Recombinant Human Cytochrome P450 4F2 isozyme microsomes, with P450 Reductase and cytochrome b5 was expressed in baculovirus infected insect cells.

Specification

• Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away.
• Source: baculovirus infected insect cells
• Species: Human
• Form: Solution in 100 mM potassium phosphate buffer, pH 7.4.
• Bio-activity: The CYP4F2 isoform catalyzes the 20-hydroxylation of leukotriene B4.
• Storage: ?70°C

Gene Information

• Gene Name: CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 [ Homo sapiens (human) ]
• Official Symbol: CYP4F2
• Synonyms: CYP4F2; CPF2; cytochrome P450, family 4, subfamily F, polypeptide 2; leukotriene-B(4) omega-hydroxylase 1; CYPIVF2; cytochrome P450 4F2; cytochrome P450-LTB-omega; leukotriene-B4 20-monooxygenase; leukotriene B4 omega-hydroxylase; leukotriene-B(4) 20-monooxygenase 1; cytochrome P450, subfamily IVF, polypeptide 2; NP_001073.3; EC 1.14.13.30
• Gene ID: 8529
• mRNA Refseq: NM_001082
• Protein Refseq: NP_001073
• MIM: 604426
• UniProt ID: P78329
• Chromosome Location: 19p13.12
• Pathway: Arachidonic acid metabolism; Biological oxidations; Miscellaneous substrates
• Function: alkane 1-monooxygenase activity; alpha-tocopherol omega-hydroxylase activity; heme binding