Recombinant Human CYP4F2


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Recombinant Human CYP4F2

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Cat.No. : CYP4F2-555H
Product Overview : Recombinant Human Cytochrome P450 4F2 isozyme microsomes, with P450 Reductase and cytochrome b5 was expressed in baculovirus infected insect cells.
Description : This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away.
Source : baculovirus infected insect cells
Species : Human
Form : Solution in 100 mM potassium phosphate buffer, pH 7.4.
Bio-activity : The CYP4F2 isoform catalyzes the 20-hydroxylation of leukotriene B4.
Storage : ?70°C
Gene Name : CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 [ Homo sapiens (human) ]
Official Symbol : CYP4F2
Synonyms : CYP4F2; CPF2; cytochrome P450, family 4, subfamily F, polypeptide 2; leukotriene-B(4) omega-hydroxylase 1; CYPIVF2; cytochrome P450 4F2; cytochrome P450-LTB-omega; leukotriene-B4 20-monooxygenase; leukotriene B4 omega-hydroxylase; leukotriene-B(4) 20-monooxygenase 1; cytochrome P450, subfamily IVF, polypeptide 2; NP_001073.3; EC
Gene ID : 8529
mRNA Refseq : NM_001082
Protein Refseq : NP_001073
MIM : 604426
UniProt ID : P78329
Chromosome Location : 19p13.12
Pathway : Arachidonic acid metabolism; Biological oxidations; Miscellaneous substrates
Function : alkane 1-monooxygenase activity; alpha-tocopherol omega-hydroxylase activity; heme binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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