Native Human KRT19

• Cat.No.: KRT19-382H
• Product Overview: Native Human KRT19 was purified from Human Tissue Culture Cell Line.

Specification

• Description: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
• Source: Human Tissue Culture Cell Line
• Species: Human
• Form: Liquid in PBS buffer
• Purity: >95% (SDS-PAGE)
• Optimum pH: 7.4
• Storage: Store at -20 °C
• Concentration: >0.01 mg/mL

Gene Information

• Gene Name: KRT19 keratin 19 [ Homo sapiens ]
• Official Symbol: KRT19
• Synonyms: KRT19; keratin 19; keratin, type I cytoskeletal 19; 40 kDa keratin intermediate filament; CK19; cytokeratin 19; K1CS; K19; keratin; type I cytoskeletal 19; type I; 40 kd; MGC15366; CK-19; keratin-19; cytokeratin-19; keratin, type I, 40-kd; 40-kDa keratin
• Gene ID: 3880
• mRNA Refseq: NM_002276
• Protein Refseq: NP_002267
• MIM: 148020
• UniProt ID: P08727
• Chromosome Location: 17q21-q23
• Pathway: Signaling mediated by p38-alpha and p38-beta, organism-specific biosystem
• Function: protein binding; structural constituent of cytoskeleton; structural constituent of muscle