Recombinant Human PPAP2B, GST-tagged
| Cat.No. : |
PPAP2B-28H |
| Product Overview : |
Recombinant Human PPAP2B(1 a.a. - 311 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
| Description : |
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. |
| Source : |
Wheat germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
59.95 kDa |
| AA Sequence : |
MQNYKYDKAIVPESKNGGSPALNNN PRRSGSKRVLLICLDLFCLFMAGLP FLIIETSTIKPYHRGFYCNDESIKY PLKTGETINDAVLCAVGIVIAILAI ITGEFYRIYYLKKSRSTIQNPYVAA LYKQVGCFLFGCAISQSFTDIAKVS IGRLRPHFLSVCNPDFSQINCSEGY IQNYRCRGDDSKVQEARKSFFSGHA SFSMYTMLYLVLYLQARFTWRGARL LRPLLQFTLIMMAFYTGLSRVSDHK HHPSDVLAGFAQGALVACCIVFFVS DLFKTKMTLSLPAPAIRKEILSPVD IIDRNNHHNMM |
| Applications : |
ELISA; WB-Re; AP; Array |
| Storage : |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Gene Name : |
PPAP2B phosphatidic acid phosphatase type 2B [ Homo sapiens ] |
| Official Symbol : |
PPAP2B |
| Synonyms : |
PPAP2B; LPP3; VCIP; Dri42; PAP2B; phosphatidic acid phosphatase type 2B; lipid phosphate phosphohydrolase 3; PAP2 beta; phosphatidate phosphohydrolase type 2b; type-2 phosphatidic acid phosphatase-beta; vascular endothelial growth factor and type I collagen inducible; NP_003704.3; EC 3.1.3.4 |
| Gene ID : |
8613 |
| mRNA Refseq : |
NM_003713 |
| Protein Refseq : |
NP_003704 |
| MIM : |
607125 |
| UniProt ID : |
O14495 |
| Chromosome Location : |
1p32.2 |
| Pathway : |
Ether lipid metabolism; Fat digestion and absorption; Fc gamma R-mediated phagocytosis |
| Function : |
integrin binding; lipid phosphatase activity; phosphatidate phosphatase activity |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
