Recombinant Human GMCSF, His-tagged
Cat.No. : | CSF2-85H |
Product Overview : | Recombinant Human GMCSF produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 127 amino acids fragment (18-144) and having a molecular mass of 18.98 KDa Dalton with an amino-terminal hexahistidine tag. Recombinant Human GM-CSF His is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CSF2-85H |
Description : | GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile Filtered clear solution. |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Formulation : | Granulocyte Macrophage Colony Stimulating Factor-His supplied in 20mM Tris HCl (pH 8) and 50% glycerol. |
Solubility : | It is recommended to reconstitute the lyophilized Granulocyte Macrophage Colony Stimulating Factor in sterile 18 MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
Stability : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Synonyms : | CSF; GM-CSF; GMCSF; MGC131935; MGC138897; CSF2; CSF-2; MGI-1GM; Pluripoietin-alpha; Molgramostin; Sargramostim; molgramostin; sargramostim; colony stimulating factor 2; Colony-stimulating factor; granulocyte-macrophage colony stimulating factor; colony stimulating factor 2 (granulocyte-macrophage) |
Gene Name : | CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Homo sapiens ] |
Gene ID : | 1437 |
mRNA Refseq : | NM_000758 |
Protein Refseq : | NP_000749 |
MIM : | 138960 |
UniProt ID : | P04141 |
Chromosome Location : | 5q31.1 |
Pathway : | Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; T cell receptor signaling pathway |
Function : | cytokine activity; granulocyte macrophage colony-stimulating factor receptor binding; growth factor activity; protein binding |
Products Types
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionThe sequence of CSF2 is moderately conserved across different species.
The length of CSF2 protein varies but is typically around 144 amino acids.
The primary function of CSF2 is to regulate the production and differentiation of white blood cells.
CSF2 is often expressed in immune cells, specifically in macrophages, T cells, and endothelial cells.
CSF2 stands for Colony Stimulating Factor 2.
CSF2 dysregulation has been linked to autoimmune diseases and inflammatory disorders.
CSF2 is involved in the stimulation of stem cells to produce granulocytes and monocytes.
Customer Reviews (3)
Write a reviewThe product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.
The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.
Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.
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