Recombinant Human ILK, MYC/DDK-tagged

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Recombinant Human ILK, MYC/DDK-tagged

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Cat.No. : ILK-12H
Product Overview : Recombinant Human ILK, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.
Description : This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
Source : HEK293 cells
Species : Human
Tag : MYC/DDK
Molecular Mass : 51.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Figure :

Gene Name : ILK integrin-linked kinase [ Homo sapiens (human) ]
Official Symbol : ILK
Synonyms : ILK-1; ILK-2; 59 kDa serine/threonine-protein kinase; p59; p59ILK; ILK; integrin-linked kinase; P59; DKFZp686F1765; ILK; integrin-linked kinase; EC 2.7.11.1; ILK2
Gene ID : 3611
mRNA Refseq : NM_001014794
Protein Refseq : NP_001014794
MIM : 602366
UniProt ID : Q13418
Chromosome Location : 11p15.4
Pathway : Bacterial invasion of epithelial cells; Cell junction organization; Cell-extracellular matrix interactions
Function : ATP binding; SH3 domain binding; integrin binding

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