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Recombinant Human FOXM1 293 Cell Lysate

Cat.No. : FOXM1-6153HCL
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  • Gene Information
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Description : Antigen standard for forkhead box M1 (FOXM1), transcript variant 2 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
Source : HEK 293 cells
Species : Human
Components : This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Size : 0.1 mg
Storage Instruction : Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Applications : ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Gene Name : FOXM1 forkhead box M1 [ Homo sapiens ]
Official Symbol : FOXM1
Synonyms : FOXM1; forkhead box M1; FKHL16; forkhead box protein M1; HFH 11; HNF 3; INS 1; M phase phosphoprotein 2; MPHOSPH2; MPP2; TGT3; trident; M-phase phosphoprotein 2; HNF-3/fork-head homolog 11; transcription factor Trident; MPM-2 reactive phosphoprotein 2; forkhead-related protein FKHL16; winged-helix factor from INS-1 cells; Forkhead, drosophila, homolog-like 16; hepatocyte nuclear factor 3 forkhead homolog 11; HFH11; HNF-3; INS-1; MPP-2; PIG29; FOXM1B; HFH-11; TRIDENT;
Gene ID : 2305
mRNA Refseq : NM_021953
Protein Refseq : NP_068772
MIM : 602341
UniProt ID : Q08050
Chromosome Location : 12p13
Pathway : FOXM1 transcription factor network, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem;
Function : DNA binding; DNA binding; DNA binding, bending; double-stranded DNA binding; protein binding; protein domain specific binding; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; transcription factor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there a relationship between the structure and function of FOXM1? 11/28/2022

The structure of FOXM1 determines its ability to bind to DNA and regulate transcription. The study of its structure can help us understand its function and mechanism of action.

What is the correlation between the expression level of FOXM1 and disease? 06/23/2021

Studies have shown that the expression level of FOXM1 is associated with the occurrence and development of a variety of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.

How to detect FOXM1 expression level? 04/29/2021

The expression level of FOXM1 can be detected by immunohistochemistry, western blot and real-time quantitative PCR.

Does FOXM1 play a role in cancer? 03/29/2021

Studies have shown that the expression level of FOXM1 is upregulated in some cancers, which may promote the occurrence and development of cancer. It could be a potential target for cancer treatment.

What factors should be considered in drug development for FOXM1? 08/13/2020

Drug development for FOXM1 requires consideration of its specificity, safety, pharmacokinetic properties, and potential side effects. In addition, issues such as the dosage form, route of administration and design of clinical trials need to be considered.

How does FOXM1 interact with other proteins? 01/04/2020

FOXM1 can interact with a variety of other proteins, including transcription factors and proteins in signal transduction pathways. These interactions enable it to regulate processes such as cell proliferation, differentiation, and apoptosis.

Customer Reviews (3)

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Reviews
08/06/2023

    Stable performance in common colorimetric reactions.

    10/01/2022

      The quality of the FOXM1 is consistent and reassuring.

      07/17/2022

        Under the influence of temperature, humidity and light, this protein has good stability and persistence.

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