Recombinant Human FOXM1 293 Cell Lysate
Cat.No. : | FOXM1-6153HCL |
- Specification
- Gene Information
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Description : | Antigen standard for forkhead box M1 (FOXM1), transcript variant 2 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Gene Name : | FOXM1 forkhead box M1 [ Homo sapiens ] |
Official Symbol : | FOXM1 |
Synonyms : | FOXM1; forkhead box M1; FKHL16; forkhead box protein M1; HFH 11; HNF 3; INS 1; M phase phosphoprotein 2; MPHOSPH2; MPP2; TGT3; trident; M-phase phosphoprotein 2; HNF-3/fork-head homolog 11; transcription factor Trident; MPM-2 reactive phosphoprotein 2; forkhead-related protein FKHL16; winged-helix factor from INS-1 cells; Forkhead, drosophila, homolog-like 16; hepatocyte nuclear factor 3 forkhead homolog 11; HFH11; HNF-3; INS-1; MPP-2; PIG29; FOXM1B; HFH-11; TRIDENT; |
Gene ID : | 2305 |
mRNA Refseq : | NM_021953 |
Protein Refseq : | NP_068772 |
MIM : | 602341 |
UniProt ID : | Q08050 |
Chromosome Location : | 12p13 |
Pathway : | FOXM1 transcription factor network, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem; |
Function : | DNA binding; DNA binding; DNA binding, bending; double-stranded DNA binding; protein binding; protein domain specific binding; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; transcription factor binding; |
Products Types
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FOXM1-4464H | Recombinant Human FOXM1 Protein, GST-tagged | +Inquiry |
Foxm1-1522M | Recombinant Mouse Foxm1 Protein, His-tagged | +Inquiry |
FOXM1-3162H | Recombinant Human FOXM1 protein, His-tagged | +Inquiry |
◆ Lysates | ||
FOXM1-6152HCL | Recombinant Human FOXM1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe structure of FOXM1 determines its ability to bind to DNA and regulate transcription. The study of its structure can help us understand its function and mechanism of action.
Studies have shown that the expression level of FOXM1 is associated with the occurrence and development of a variety of diseases, including cancer, cardiovascular disease, and neurodegenerative diseases.
The expression level of FOXM1 can be detected by immunohistochemistry, western blot and real-time quantitative PCR.
Studies have shown that the expression level of FOXM1 is upregulated in some cancers, which may promote the occurrence and development of cancer. It could be a potential target for cancer treatment.
Drug development for FOXM1 requires consideration of its specificity, safety, pharmacokinetic properties, and potential side effects. In addition, issues such as the dosage form, route of administration and design of clinical trials need to be considered.
FOXM1 can interact with a variety of other proteins, including transcription factors and proteins in signal transduction pathways. These interactions enable it to regulate processes such as cell proliferation, differentiation, and apoptosis.
Customer Reviews (3)
Write a reviewStable performance in common colorimetric reactions.
The quality of the FOXM1 is consistent and reassuring.
Under the influence of temperature, humidity and light, this protein has good stability and persistence.
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