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Recombinant Human BIRC7 293 Cell Lysate

Cat.No. : BIRC7-8448HCL
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  • Gene Information
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Description : Antigen standard for baculoviral IAP repeat-containing 7 (BIRC7), transcript variant 1 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
Source : HEK 293 cells
Species : Human
Components : This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Size : 0.1 mg
Storage Instruction : Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Applications : ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Gene Name : BIRC7 baculoviral IAP repeat containing 7 [ Homo sapiens ]
Official Symbol : BIRC7
Synonyms : BIRC7; baculoviral IAP repeat containing 7; baculoviral IAP repeat-containing protein 7; KIAP; kidney inhibitor of apoptosis protein; livin; livin inhibitor of apoptosis; melanoma inhibitor of apoptosis protein; ML IAP; mliap; RNF50; RING finger protein 50; LIVIN; MLIAP; ML-IAP;
Gene ID : 79444
mRNA Refseq : NM_139317
Protein Refseq : NP_647478
MIM : 605737
UniProt ID : Q96CA5
Chromosome Location : 20q13.3
Pathway : Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Pathways in cancer, organism-specific biosystem; Small cell lung cancer, organism-specific biosystem; Small cell lung cancer, conserved biosystem;
Function : cysteine-type endopeptidase inhibitor activity; enzyme binding; metal ion binding; protein binding; ubiquitin-protein ligase activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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How can BIRC7 be used to treat cancer? 09/22/2022

In response to the role of BIRC7 in cancer, some therapeutics can be developed, such as inhibitors or antibodies targeting BIRC7, which are used to inhibit the proliferation and survival of tumor cells and enhance the attack ability of the immune system.

How does BIRC7 correlate with other genes? 09/07/2022

It has complex associations with other genes and may interact with multiple genes to participate in biochemical processes such as apoptosis.

What are the mutation types in BIRC7? 06/22/2022

The types of mutations in BIRC7 include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

What is the role of BIRC7 in cancer? 09/04/2021

BIRC7 has a dual role in cancer, on the one hand, it can promote the proliferation and survival of tumor cells, and on the other hand, it can also suppress the immune response and help tumor cells evade the attack of the immune system.

How to study the regulatory mechanism of BIRC7? 12/07/2020

Studying the regulatory mechanism of BIRC7 requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Can the expression pattern of BIRC7 be used for disease diagnosis? 09/26/2020

By detecting the expression pattern of BIRC7, it can assist in the diagnosis of certain diseases, such as cancer, neurodegenerative diseases, etc.

Customer Reviews (3)

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10/27/2022

    High solubility, fast dissolution, good adaptability to solvents.

    01/09/2022

      BIRC7 has performed well in various experiments and is a reliable choice.

      12/22/2021

        Very suitable for biological activity experiment, good activity.

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