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Recombinant Human RUVBL2, GST tagged

Cat.No. : RUVBL2-2475H
Product Overview : Recombinant Human RUVBL2 full-length ORF ( AAH00428, 1 a.a. - 463 a.a.) was expressed in Wheat Germ with GST-tag at N-terminal.
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Description : This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
Source : Wheat Germ (in vitro)
Species : Human
Tag : GST
Form : Liquid
Molecular Mass : 76.67 kDa
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : RUVBL2 RuvB-like 2 (E. coli) [ Homo sapiens ]
Official Symbol : RUVBL2
Synonyms : RUVBL2; RuvB-like 2 (E. coli); RuvB (E coli homolog) like 2; ruvB-like 2; ECP51; INO80 complex subunit J; INO80J; reptin; Reptin52; Rvb2; RVB2; TIH2; TIP48; TIP49b; ECP-51; reptin 52; TAP54-beta; reptin52 protein; repressing pontin 52; RuvB (E coli homolog)-like 2; 48 kDa TBP-interacting protein; TBP-interacting protein, 48-KD; TIP60-associated protein 54-beta; 51 kDa erythrocyte cytosolic protein; erythrocyte cytosolic protein, 51-KD; 48 kDa TATA box-binding protein-interacting protein; CGI-46; REPTIN; TIP49B;
Gene ID : 10856
mRNA Refseq : NM_006666
Protein Refseq : NP_006657
MIM : 604788
UniProt ID : Q9Y230
Chromosome Location : 19q13.3
Pathway : ATF-2 transcription factor network, organism-specific biosystem; C-MYC pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Extension of Telomeres, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; Telomere Extension By Telomerase, organism-specific biosystem;
Function : ATP binding; ATP-dependent DNA helicase activity; contributes_to ATPase activity; DNA helicase activity; damaged DNA binding; hydrolase activity; identical protein binding; identical protein binding; nucleotide binding; protein binding; unfolded protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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