Recombinant Human ADARB1 cell lysate


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Recombinant Human ADARB1 cell lysate

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Cat.No. : ADARB1-28HCL
Description : This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : ADARB1 adenosine deaminase, RNA-specific, B1 [ Homo sapiens ]
Official Symbol : ADARB1
Synonyms : ADARB1; adenosine deaminase, RNA-specific, B1; adenosine deaminase, RNA specific, B1 (homolog of rat RED1); double-stranded RNA-specific editase 1; ADAR2; ADAR2a; ADAR2a L1; ADAR2a L2; ADAR2a L3; ADAR2b; ADAR2c; ADAR2d; ADAR2g; DRABA2; DRADA2; hRED1; RED1; RED1 homolog (rat); RNA editase; RED1 homolog; RNA-editing enzyme 1; RNA editing deaminase 1; RNA-editing deaminase 1; dsRNA adenosine deaminase; human dsRNA adenosine deaminase DRADA2; adenosine deaminase, RNA-specific, B1 (RED1 homolog rat); adenosine deaminase, RNA-specific, B1 (homolog of rat RED1);
Gene ID : 104
mRNA Refseq : NM_001112
Protein Refseq : NP_001103
MIM : 601218
UniProt ID : P78563
Chromosome Location : 21q22.3
Pathway : C6 deamination of adenosine, organism-specific biosystem; Formation of editosomes by ADAR proteins, organism-specific biosystem; Gene Expression, organism-specific biosystem; mRNA Editing, organism-specific biosystem; mRNA Editing: A to I Conversion, organism-specific biosystem;
Function : RNA binding; adenosine deaminase activity; double-stranded RNA adenosine deaminase activity; double-stranded RNA binding; double-stranded RNA binding; hydrolase activity; mRNA binding; metal ion binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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