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Recombinant Human ADRB2 cell lysate

Cat.No.: ADRB2-34HCL
Description: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: ADRB2 adrenoceptor beta 2, surface [ Homo sapiens ]
Official Symbol: ADRB2
Synonyms: BAR; B2AR; ADRBR; ADRB2R; BETA2AR; beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor; catecholamine receptoradrenoceptor beta 2 surface; adrenergic, beta-2-, receptor, surface
Gene ID: 154
mRNA Refseq: NM_000024
Protein Refseq: NP_000015
MIM: 109690
UniProt ID: P07550
Chromosome Location: 5q31-q32
Pathway: Adrenergic signaling in cardiomyocytes, organism-specific biosystem; Arf6 signaling events, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem
Function: adenylate cyclase binding; beta2-adrenergic receptor activity; norepinephrine binding

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