Recombinant Human ANAPC5 cell lysate
Cat.No. : | ANAPC5-74HCL |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | ANAPC5 anaphase promoting complex subunit 5 [ Homo sapiens ] |
Official Symbol : | ANAPC5 |
Synonyms : | ANAPC5; anaphase promoting complex subunit 5; anaphase-promoting complex subunit 5; APC5; cyclosome subunit 5; |
Gene ID : | 51433 |
mRNA Refseq : | NM_001137559 |
Protein Refseq : | NP_001131031 |
MIM : | 606948 |
UniProt ID : | Q9UJX4 |
Chromosome Location : | 12q24 |
Pathway : | APC/C complex, organism-specific biosystem; APC/C complex, conserved biosystem; APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; |
Function : | binding; protein phosphatase binding; ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
ANAPC5-1211H | Recombinant Human ANAPC5 Protein (2-232 aa), GST-tagged | +Inquiry |
Anapc5-1622M | Recombinant Mouse Anapc5 Protein, Myc/DDK-tagged | +Inquiry |
ANAPC5-2085H | Recombinant Human ANAPC5 Protein, MYC/DDK-tagged | +Inquiry |
ANAPC5-339H | Recombinant Human ANAPC5 Protein, His (Fc)-Avi-tagged | +Inquiry |
ANAPC5-321R | Recombinant Rat ANAPC5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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