Recombinant Human ANAPC5 Protein (2-232 aa), GST-tagged

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Recombinant Human ANAPC5 Protein (2-232 aa), GST-tagged

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Cat.No. : ANAPC5-1211H
Product Overview : Recombinant Human ANAPC5 Protein (2-232 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Cell Cycle. Protein Description: Partial.
Description : Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Source : E. coli
Species : Human
Tag : GST
Form : Tris-based buffer,50% glycerol
Molecular Mass : 53.2 kDa
Protein length : 2-232 aa
AA Sequence : ASVHESLYFN PMMTNGVVHA NVFGIKDWVT PYKIAVLVLL NEMSRTGEGA VSLMERRRLN QLLLPLLQGP DITLSKLYKL IEESCPQLAN SVQIRIKLMA EGELKDMEQF FDDLSDSFSG TEPEVHKTSV VGLFLRHMIL AYSKLSFSQV FKLYTALQQY FQNGEKKTVE DADMELTSRD EGERKMEKEE LDVSVREEEV SCSGPLSQKQ AEFFLSQQAS LLKNDETKAL T
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : ANAPC5 anaphase promoting complex subunit 5 [ Homo sapiens ]
Official Symbol : ANAPC5
Synonyms : ANAPC5; APC5; cyclosome subunit 5;
Gene ID : 51433
mRNA Refseq : NM_001137559
Protein Refseq : NP_001131031
MIM : 606948
UniProt ID : Q9UJX4

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