Recombinant Human CBFA2T3 cell lysate
- Specification
- Gene Information
- Related Products
| Description : |
The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5-region of the AML1 gene fused to the 3-region of this gene. In addition, this gene is a putative breast tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene, and a brefeldin A-sensitive association of RII-alpha protein with one of the isoforms has been demonstrated in the Golgi apparatus. |
| Species : |
Human |
| Size : |
100 ul |
| Storage Buffer : |
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
| Applications : |
Western Blot; |
| Gene Name : |
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 [ Homo sapiens ] |
| Official Symbol : |
CBFA2T3 |
| Synonyms : |
CBFA2T3; core-binding factor, runt domain, alpha subunit 2; translocated to, 3; protein CBFA2T3; MTG16; MTGR2; myeloid translocation gene 8 and 16b; ZMYND4; MTG8-related gene 2; MTG8-related protein 2; zinc finger MYND domain-containing protein 4; myeloid translocation gene on chromosome 16 protein; ETO2; |
| Gene ID : |
863 |
| mRNA Refseq : |
NM_005187 |
| Protein Refseq : |
NP_005178 |
| MIM : |
603870 |
| UniProt ID : |
O75081 |
| Chromosome Location : |
16q24 |
| Pathway : |
ErbB4 signaling events, organism-specific biosystem; |
| Function : |
chromatin binding; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; zinc ion binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
