Recombinant Human EIF4G1 cell lysate

• Cat.No.: EIF4G1-545HCL

Specification

• Description: The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 [ Homo sapiens ]
• Official Symbol: EIF4G1
• Synonyms: EIF4G1; eukaryotic translation initiation factor 4 gamma, 1; EIF4F, EIF4G; eukaryotic translation initiation factor 4 gamma 1; p220; EIF4-gamma; eIF-4-gamma 1; eucaryotic translation initiation factor 4G; P220; EIF4F; EIF4G; EIF4GI; PARK18; EIF-4G1; DKFZp686A1451
• Gene ID: 1981
• mRNA Refseq: NM_001194946
• Protein Refseq: NP_001181875
• MIM: 600495
• UniProt ID: Q04637
• Chromosome Location: 3q27-qter
• Pathway: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Deadenylation of mRNA, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem
• Function: protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity