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Recombinant Human HMGCS2 cell lysate

Cat.No. : HMGCS2-804HCL
  • Specification
  • Gene Information
  • Related Products
Description : Mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase (HMGCS2; EC 2.3.3.10) mediates the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for brain, heart, kidney, and other organs during times of carbohydrate deprivation such as fasting (Robinson and Williamson, 1980 [PubMed 6986618]). Also see cytoplasmic HMG-CoA synthase (HMGCS1; MIM 142940), which mediates an early step in cholesterol synthesis.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) [ Homo sapiens ]
Official Symbol : HMGCS2
Synonyms : HMGCS2; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial); hydroxymethylglutaryl-CoA synthase, mitochondrial; HMG-CoA synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial);
Gene ID : 3158
mRNA Refseq : NM_001166107
Protein Refseq : NP_001159579
MIM : 600234
UniProt ID : P54868
Chromosome Location : 1p13-p12
Pathway : Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Ketone body metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem;
Function : hydroxymethylglutaryl-CoA synthase activity; transferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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