"IYD" Related Products


Recombinant Human IYD cell lysate

Cat.No.: IYD-885HCL
Description: This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: IYD iodotyrosine deiodinase [ Homo sapiens ]
Official Symbol: IYD
Synonyms: TDH4; DEHAL1; C6orf71; dJ422F24.1; iodotyrosine dehalogenase 1; IYD-1
Gene ID: 389434
mRNA Refseq: NM_001164694
Protein Refseq: NP_001158166
MIM: 612025
UniProt ID: Q6PHW0
Chromosome Location: 6q25.1
Pathway: Amine-derived hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Thyroxine biosynthesis, organism-specific biosystem
Function: iodide peroxidase activity; oxidoreductase activity

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