Recombinant Human IYD Protein, GST-tagged
Cat.No. : | IYD-4938H |
Product Overview : | Human IYD full-length ORF ( NP_981932.1, 1 a.a. - 289 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 59.8 kDa |
AA Sequence : | MYFLTPILVAILCILVVWIFKNADR SMEKKKGEPRTRAEARPWVDEDLKD SSDLHQAEEDADEWQESEENVEHIP FSHNHYPEKEMVKRSQEFYELLNKR RSVRFISNEQVPMEVIDNVIRTAGT APSGAHTEPWTFVVVKDPDVKHKIR KIIEEEEEINYMKRMGHRWVTDLKK LRTNWIKEYLDTAPILILIFKQVHG FAANGKKKVHYYNEISVSIACGILL AALQNAGLVTVTTTPLNCGPRLRVL LGRPAHEKLLMLLPVGYPSKEATVP DLKRKPLDQIMVTV |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | IYD iodotyrosine deiodinase [ Homo sapiens (human) ] |
Official Symbol : | IYD |
Synonyms : | IYD; iodotyrosine deiodinase; TDH4; IYD-1; DEHAL1; C6orf71; iodotyrosine deiodinase 1; iodotyrosine dehalogenase 1; EC 1.21.1.1 |
Gene ID : | 389434 |
mRNA Refseq : | NM_001164694 |
Protein Refseq : | NP_001158166 |
MIM : | 612025 |
UniProt ID : | Q6PHW0 |
Products Types
◆ Recombinant Protein | ||
IYD-2788R | Recombinant Rat IYD Protein, His (Fc)-Avi-tagged | +Inquiry |
IYD-4663M | Recombinant Mouse IYD Protein, His (Fc)-Avi-tagged | +Inquiry |
IYD-495H | Recombinant Human iodotyrosine deiodinase, His-tagged | +Inquiry |
IYD-8401M | Recombinant Mouse IYD Protein | +Inquiry |
IYD-5096H | Recombinant Human IYD, His-tagged | +Inquiry |
◆ Lysates | ||
IYD-885HCL | Recombinant Human IYD cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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