Recombinant Human MSX2 cell lysate
- Specification
- Gene Information
- Related Products
Description : |
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. |
Species : |
Human |
Size : |
100 ul |
Storage Buffer : |
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : |
Western Blot; |
Gene Name : |
MSX2 msh homeobox 2 [ Homo sapiens ] |
Official Symbol : |
MSX2 |
Synonyms : |
MSX2; msh homeobox 2; msh (Drosophila) homeo box homolog 2 , msh homeobox homolog 2 (Drosophila) , parietal foramina 1 , PFM1; homeobox protein MSX-2; craniosynostosis; type 2; CRS2; FPP; HOX8; MSH; PFM; msh homeo box 2; homeobox protein Hox-8; msh homeobox homolog 2; PFM1; |
Gene ID : |
4488 |
mRNA Refseq : |
NM_002449 |
Protein Refseq : |
NP_002440 |
MIM : |
123101 |
UniProt ID : |
P35548 |
Chromosome Location : |
5q35.2 |
Pathway : |
HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; |
Function : |
protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.