Recombinant Human MTMR3 cell lysate
Cat.No. : | MTMR3-1148HCL |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | MTMR3 myotubularin related protein 3 [ Homo sapiens ] |
Official Symbol : | MTMR3 |
Synonyms : | MTMR3; myotubularin related protein 3; myotubularin-related protein 3; FYVE DSP1; KIAA0371; ZFYVE10; zinc finger, FYVE domain containing 10; zinc finger FYVE domain-containing protein 10; FYVE domain-containing dual specificity protein phosphatase 1; FYVE (Fab1 YGLO23 Vsp27 EEA1 domain) dual-specificity protein phosphatase; FYVE-DSP1; FLJ32333; |
Gene ID : | 8897 |
mRNA Refseq : | NM_021090 |
Protein Refseq : | NP_066576 |
MIM : | 603558 |
UniProt ID : | Q13615 |
Chromosome Location : | 22q12.2 |
Pathway : | 3-phosphoinositide degradation, organism-specific biosystem; 3-phosphoinositide degradation, conserved biosystem; D-myo-inositol-5-phosphate metabolism, organism-specific biosystem; D-myo-inositol-5-phosphate metabolism, conserved biosystem; superpathway of inositol phosphate compounds, organism-specific biosystem; |
Function : | hydrolase activity; metal ion binding; phosphatidylinositol-3-phosphatase activity; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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