Recombinant Human OPA1 cell lysate
- Specification
- Gene Information
- Related Products
| Description : |
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Species : |
Human |
| Size : |
100 ul |
| Storage Buffer : |
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
| Applications : |
Western Blot; |
| Gene Name : |
OPA1 optic atrophy 1 (autosomal dominant) [ Homo sapiens ] |
| Official Symbol : |
OPA1 |
| Synonyms : |
OPA1; optic atrophy 1 (autosomal dominant); dynamin-like 120 kDa protein, mitochondrial; dynamin like guanosine triphosphatase; FLJ12460; KIAA0567; MGM1; mitochondrial dynamin like GTPase; NPG; NTG; optic atrophy protein 1; mitochondrial dynamin-like GTPase; dynamin-like guanosine triphosphatase; mitochondrial dynamin-like 120 kDa protein; largeG; |
| Gene ID : |
4976 |
| mRNA Refseq : |
NM_015560 |
| Protein Refseq : |
NP_056375 |
| MIM : |
605290 |
| UniProt ID : |
O60313 |
| Chromosome Location : |
3q28-q29 |
| Function : |
GTP binding; GTPase activity; magnesium ion binding; nucleotide binding; protein binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
