Recombinant Human OPA1 cell lysate

• Cat.No.: OPA1-1251HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: OPA1 optic atrophy 1 (autosomal dominant) [ Homo sapiens ]
• Official Symbol: OPA1
• Synonyms: OPA1; optic atrophy 1 (autosomal dominant); dynamin-like 120 kDa protein, mitochondrial; dynamin like guanosine triphosphatase; FLJ12460; KIAA0567; MGM1; mitochondrial dynamin like GTPase; NPG; NTG; optic atrophy protein 1; mitochondrial dynamin-like GTPase; dynamin-like guanosine triphosphatase; mitochondrial dynamin-like 120 kDa protein; largeG
• Gene ID: 4976
• mRNA Refseq: NM_015560
• Protein Refseq: NP_056375
• MIM: 605290
• UniProt ID: O60313
• Chromosome Location: 3q28-q29
• Function: GTP binding; GTPase activity; magnesium ion binding; nucleotide binding; protein binding