Recombinant Human PKP1 cell lysate
- Specification
- Gene Information
- Related Products
| Description : |
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. |
| Species : |
Human |
| Size : |
100 ul |
| Storage Buffer : |
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
| Applications : |
Western Blot; |
| Gene Name : |
PKP1 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) [ Homo sapiens ] |
| Official Symbol : |
PKP1 |
| Synonyms : |
PKP1; plakophilin 1 (ectodermal dysplasia/skin fragility syndrome); plakophilin-1; B6P; band 6 protein; MGC138829; |
| Gene ID : |
5317 |
| mRNA Refseq : |
NM_000299 |
| Protein Refseq : |
NP_000290 |
| MIM : |
601975 |
| UniProt ID : |
Q13835 |
| Chromosome Location : |
1q32 |
| Pathway : |
Apoptosis, organism-specific biosystem; Apoptotic cleavage of cell adhesionproteins, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; |
| Function : |
binding; intermediate filament binding; signal transducer activity; structural constituent of epidermis; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
