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Recombinant Human PKP1 protein, His & GST-tagged

Cat.No. : PKP1-1975H
Product Overview : Recombinant Human PKP1 aa. (Asn500~Asn742 (Accession # Q13835)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 58.8kDa
Protein length : Asn500~Asn742 (Accession # Q13835)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Characteristic : The isoelectric point is 8.4.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : PKP1 plakophilin 1 [ Homo sapiens (human) ]
Official Symbol : PKP1
Synonyms : Cyp24a1; cytochrome P450, family 24, subfamily a, polypeptide 1; CP24; Cyp24; 24-OHase; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 25-hydroxyvitamin D-24-hydroxylase; cytochrome P450 24A1; cytochrome P450, 24; cytochrome P450, 24a1; cytochrome P450-CC24; vitamin D(3) 24-hydroxylase
Gene ID : 5317
mRNA Refseq : NM_000299.3
Protein Refseq : NP_000290.2
UniProt ID : Q13835

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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