"PPY" Related Products

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Recombinant Human PPY cell lysate

Cat.No.: PPY-1408HCL
Description: This gene belongs to the NPY family and it encodes a protein that is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: PPY pancreatic polypeptide [ Homo sapiens ]
Official Symbol: PPY
Synonyms: PPY; pancreatic polypeptide; pancreatic prohormone; pancreatic polypeptide Y; PNP; PP;
Gene ID: 5539
mRNA Refseq: NM_002722
Protein Refseq: NP_002713
MIM: 167780
UniProt ID: P01298
Chromosome Location: 17p11.1-qter
Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem;
Function: G-protein coupled receptor binding; hormone activity; receptor binding;

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